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ACROBiosystems Human B7-H2 / ICOSLG Protein, Fc Tag
4578.60 NOK - 33576.41 NOK
Specifications
| Accession Number | NP_056074.1 |
|---|---|
| Molecular Weight (g/mol) | 53.1 kDa |
| Source | Human B7-H2, Fc Tag (B72-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Ser 258 (Accession # O75144-1). |
| Immunogen | Asp 19 - Ser 258 |
| Storage Requirements | -20°C |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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16457179
|
ACROBiosystems
B72-H5254-1MG |
1 mg |
33576.41 NOK
1mg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
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|
16447179
|
ACROBiosystems
B72-H5254-100UG |
100 μg |
4578.60 NOK
100µg |
Estimated Shipment: 30-04-2024 Log in to see stock. |
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Description
ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related protein 1 (B7RP-1) and CD antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.1 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_056074.1 | |
| Human B7-H2, Fc Tag (B72-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Ser 258 (Accession # O75144-1). | |
| -20°C | |
| B7-H2 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 53.1 kDa | |
| Asp 19 - Ser 258 | |
| ICOSLG,B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS,ICOS ligand | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |