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ACROBiosystems Human Alpha-Synuclein Protein, His Tag

2421.74 NOK - 10141.03 NOK

Specifications

Accession Number NP_000336.1
Molecular Weight (g/mol) 16.3 kDa
Source Human Alpha-Synuclein, His Tag (ALN-H52H8) is expressed from E.coli cells. It contains AA Met 1 - Ala 140 (Accession # P37840-1).
Immunogen Met 1 - Ala 140
Storage Requirements -20°C
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17106071
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ACROBiosystems
ALN-H52H8-200UG
200 μg
2421.74 NOK
200µg
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17196061
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ACROBiosystems
ALN-H52H8-1MG
1 mg
10141.03 NOK
1mg
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Estimated Shipment: 11-04-2024
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Description

Description

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.3 kDa. The protein migrates as 19 kDa under reducing (R) condition (SDS-PAGE).
Specifications

Specifications

NP_000336.1
Human Alpha-Synuclein, His Tag (ALN-H52H8) is expressed from E.coli cells. It contains AA Met 1 - Ala 140 (Accession # P37840-1).
-20°C
Alpha-Synuclein
Human
100 mM NaAC, pH7.0
E.coli
Other Recombinant Proteins
16.3 kDa
Met 1 - Ala 140
SNCA,NACP,PARK1,alpha-Synuclein
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
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