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HLA-DRB5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | HLA-DRB5 |
---|---|
Concentration | 0.17 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16891295
|
Proteintech
21702-1-AP-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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16881295
|
Proteintech
21702-1-AP-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.Specifications
HLA-DRB5 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q30154 | |
3127 | |
HLA-DRB5 Fusion Protein Ag16307 | |
Primary | |
-20°C | |
HLA-DRB5 |
0.17 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
DR beta 2, DR beta 5, Dw2, HLA DRB, HLA DRB5, HLA-DRB5, MHC class II antigen DRB5 | |
HLA-DRB5 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |