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Galectin 3 Monoclonal Antibody (eBioM3/38 (M3/38)), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1258.00 NOK - 3130.00 NOK

Specifications

Antigen Galectin 3
Clone eBioM3/38 (M3/38)
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15248799
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Affymetrix eBioscience
12-5301-82
100 μg
2095.00 NOK
100µg
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15258799
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Affymetrix eBioscience
12-5301-83
200 μg
3130.00 NOK
200µg
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Estimated Shipment: 08-05-2024
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15238799
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Affymetrix eBioscience
12-5301-81
50 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The eBioM3/38 antibody reacts with mouse Galectin-3 (Mac-2). Galectins are a family of animal lectins which appear to exhibit a variety of biological functions. Galectin 3 (aka LGALS3, galactose-specific soluble lectin 3, Mac-2, L-29) is one of the more extensively studied members of this family and is a 30 kDa beta-galactoside-binding protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homo-oligomerized. Galectin 3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. This monoclonal antibody eBioM3/38 crossreacts to human Galectin-3 (LGALS3). Applications Reported: This eBioM3/38 (M3/38) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioM3/38 (M3/38) antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal macrophages. This can be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Specifications

Specifications

Galectin 3
0.2 mg/mL
Monoclonal
Liquid
RUO
16854, 3958
IgG2a κ
Affinity chromatography
Antibody
eBioM3/38 (M3/38)
Flow Cytometry
PE
Rat
Human, Mouse
LGALS3
Primary
4° C, store in dark, DO NOT FREEZE!
LGALS3
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SDS
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For Research Use Only.