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Galectin 3 Monoclonal Antibody (eBioM3/38 (M3/38)), PE, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
1258.00 NOK - 3130.00 NOK
Specifications
Antigen | Galectin 3 |
---|---|
Clone | eBioM3/38 (M3/38) |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15248799
|
Affymetrix eBioscience
12-5301-82 |
100 μg |
2095.00 NOK
100µg |
In Stock Log in to see stock. |
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15258799
|
Affymetrix eBioscience
12-5301-83 |
200 μg |
3130.00 NOK
200µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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15238799
|
Affymetrix eBioscience
12-5301-81 |
50 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The eBioM3/38 antibody reacts with mouse Galectin-3 (Mac-2). Galectins are a family of animal lectins which appear to exhibit a variety of biological functions. Galectin 3 (aka LGALS3, galactose-specific soluble lectin 3, Mac-2, L-29) is one of the more extensively studied members of this family and is a 30 kDa beta-galactoside-binding protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homo-oligomerized. Galectin 3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. This monoclonal antibody eBioM3/38 crossreacts to human Galectin-3 (LGALS3). Applications Reported: This eBioM3/38 (M3/38) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioM3/38 (M3/38) antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal macrophages. This can be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.Specifications
Galectin 3 | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
16854, 3958 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
eBioM3/38 (M3/38) | |
Flow Cytometry | |
PE | |
Rat | |
Human, Mouse | |
LGALS3 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
LGALS3 |
For Research Use Only.