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Invitrogen™ EGFR (ErbB1) [T790M] [L858R] Recombinant Human Protein
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors.
16000.00 NOK - 69300.00 NOK
Specifications
Accession Number | NP_005219.2; T790M L858R |
---|---|
Formulation | 50mM Tris pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Polysorbate 20, 2mM DTT, 50% glycerol |
Molecular Weight (g/mol) | 90.6kDa |
Storage Requirements | Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
Regulatory Status | RUO - research use only |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15448693
|
Invitrogen™
PR8911A |
100μg |
16000.00 NOK
100µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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15418773
|
Invitrogen™
PV4880 |
1mg |
69300.00 NOK
1mg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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Description
Overexpression of EGFR has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.
Specifications
NP_005219.2; T790M L858R | |
90.6kDa | |
RUO - research use only | |
EGFR (ErbB1) T790M L858R | |
Human | |
GST Tag | |
Frozen |
50mM Tris pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Polysorbate 20, 2mM DTT, 50% glycerol | |
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. | |
Cytoplasmic | |
EGF Receptor (ErbB) Kinase Family | |
Recombinant | |
Baculovirus |