DR3, Biotin, clone: JD3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-6603-82
Additional Details : Weight : 0.25000kg
DescriptionDescription: The JD3 monoclonal antibody reacts with human DR3, also known as Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. DR3, a novel death receptor is expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand activates NF-kappa B pathway and induces apoptosis. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. JD3 has been reported for use in flow cytometric analysis.Applications Reported: The JD3 antibody has been reported for use in flow cytometric analysis.Applications Tested: The JD3 antibody has been tested by flow cytometric analysis of human peripheral leukocytes and human DR3-transfected cells. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|APO3, apoptosis inducing receptor, apoptosis-inducing receptor AIR, apoptosis-mediating receptor DR3, apoptosis-mediating receptor TRAMP, DDR3, death domain receptor 3 soluble form, death receptor beta, DR3, lymphocyte-associated receptor of death, protein WSL-1, TNFRSF12, tumor necrosis factor receptor superfamily member 25, tumor necrosis factor receptor superfamily, member 12, tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein), tumor necrosis factor receptor superfamily, member 25, WSL, WSL1|
|IgG1, kappa, kappa|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.