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Cyclopiazonic acid, 98%, Thermo Scientific™
Inhibitor of the sarco/endoplasmic reticulum calcium pump, calcium-ATPase
3125.00 NOK - 10320.00 NOK
Chemical Identifiers
| CAS | 18172-33-3 |
|---|---|
| Molecular Formula | C20H20N2O3 |
| Molecular Weight (g/mol) | 336.391 |
| MDL Number | MFCD00167445 |
| InChI Key | SZINUGQCTHLQAZ-AFAVFJNCSA-N |
| Synonym | cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020 |
| PubChem CID | 54711281 |
| SMILES | CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15464169
|
Thermo Scientific Alfa Aesar
J61594.MA |
10mg |
3125.00 NOK
10mg |
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|
15474169
|
Thermo Scientific Alfa Aesar
J61594.MF |
50mg |
10320.00 NOK
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsThe use of Cyclopiazonic acid on Langendorff-perfused murine hearts displayed anti-arrhythmic effects. Also, administration of cyclopiazonic acid on rat soleus muscle showed a decrease in hormone sensitive lipase activity and triacylglycerol hydrolysis. It is also used as an inhibitor of endoplasmic reticulum Ca2+-ATPase.
Solubility
Soluble in DMSO (100 mM), ethanol (5 mM), DMF (∼20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Keep in a dry place. Keep away from strong oxidizing agents.
Chemical Identifiers
| 18172-33-3 | |
| 336.391 | |
| SZINUGQCTHLQAZ-AFAVFJNCSA-N | |
| 54711281 |
| C20H20N2O3 | |
| MFCD00167445 | |
| cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020 | |
| CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O |
Specifications
| 18172-33-3 | |
| MFCD00167445 | |
| cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020 | |
| SZINUGQCTHLQAZ-AFAVFJNCSA-N | |
| 336.391 | |
| 336.39 | |
| Cyclopiazonic acid |
| C20H20N2O3 | |
| UN2811 | |
| Soluble in DMSO (100 mM),ethanol (5 mM),DMF (∽20mg/ml),and 1:1 DMSO:PBS(pH 7.2) (0.5mg/ml). Insoluble in water. | |
| CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O | |
| 54711281 | |
| ≥99% |
Safety and Handling
GHS H Statement
H300-H361
Fatal if swallowed.
Suspected of damaging fertility or the unborn child.
P264b-P270-P301+P310-P330-P501c
H300
missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
missing translation for 'rtecsNumber' : UY8587000
missing translation for 'tsca' : No
Recommended Storage : Store at -20°C
RUO – Research Use Only
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