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Invitrogen™ CDK2/cyclin E1 Recombinant Human Protein

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. Recombinant full-length human CDK2 and CyclinE1 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

3830.00 NOK - 58300.00 NOK

Specifications

For Use With (Application) Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
Formulation 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
Molecular Weight (g/mol) 60.2/73.4kDa
Storage Requirements Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Gene Alias CDK2: p33 (CDK2) CyclinE1: CCNE1, CCNE
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15438943
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Invitrogen™
PV6295
10μg
3830.00 NOK
10µg
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15448943
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Invitrogen™
PV6296
100μg
13020.00 NOK
100µg
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Estimated Shipment: 11-04-2024
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15458943
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Invitrogen™
PV6297
1mg
58300.00 NOK
1mg
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Estimated Shipment: 11-04-2024
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Description

Description

CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation
60.2/73.4kDa
CDK2: p33 (CDK2) CyclinE1: CCNE1, CCNE
Recombinant
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Human
GST Tag
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