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Invitrogen™ Human CDK1/cyclin A2, GST Tag Recombinant Protein
Human CDK1/cyclin A2, GST Tag Recombinant Protein
Brand: Invitrogen™ PV6280
Additional Details : Weight : 0.01000kg
Description
CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
Kinase Assay | |
10μg | |
Recombinant | |
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
|
Serine/Threonine Kinase | |
Baculovirus | |
Recombinant, Full Length |
60.4/74.8 kDa | |
Human | |
GST Tag | |
Biochemical binding/kinetic | |
CDK1/cyclin A2 | |
Kinases & Inhibitors | |
Liquid |