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CD93 (AA4.1) Monoclonal Antibody (AA4.1), FITC, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

942.00 NOK - 1686.00 NOK

Specifications

Antigen CD93 (AA4.1)
Clone AA4.1
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15258279
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Affymetrix eBioscience
11-5892-81
50 μg
942.00 NOK
50µg
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Estimated Shipment: 08-05-2024
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15268279
View Documents Promotion Details
Affymetrix eBioscience
11-5892-82
100 μg
1686.00 NOK
100µg
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Estimated Shipment: 10-04-2024
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Descrizione

Descrizione

Description: The AA4.1 monoclonal antibody reacts with mouse C1qRp, an approximately 130-140 kDa C-type lectin-like type I transmembrane protein. The AA4.1 antigen was originally identified as an antigen expressed on early stages of B cell development in bone marrow. Adult spleen and fetal liver also have detectable numbers of AA4.1 positive cells. In combination with other markers of hematopoietic progenitor cells such as Thy-1, Sca-1, c-Kit, CD43, and CD24, the bone marrow Lymphoid-Committed Progenitors (CLP) can be segregated into more primitive and more differentiated subsets based on expression of AA4.1. Correlated expression of surface IgM (sIgM), CD23, and AA4.1 antigen has also been used to define three nonproliferative subpopulations of immature/transitional peripheral B cells designated: T1 (AA4.1+/CD23-/sIgMhi), T2 (AA4.1+/CD23+/sIgMhi), and T3 (AA4.1+/CD23+/sIgMlo). AA4.1 is also reported to be expressed in cytoplasmic vesicles in endothelial cells, megakaryoblasts, and platelets. It is reported that monoclonal antibodies AA4.1 and 493 recognize different epitopes of the same molecule. Applications Reported: The AA4.1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This AA4.1 antibody has been tested by flow cytometric analysis of mouse bone marrow cells or splenocytes. This can be used at less than or equal to 1 μg per test.

The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Specifica

Specifica

CD93 (AA4.1)
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
6030404G09Rik; AA145088; Aa4; AA4.1; AW555904; C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; C1qR(P); C1qr1; C1qRP; Cd93; CD93 antigen; CD93 molecule; CDw93; Cell surface antigen AA4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; ly-68; Lymphocyte antigen 68; matrix-remodeling-associated protein 4; matrix-remodelling associated 4; MXRA4
Cd93
Primary
4° C, store in dark, DO NOT FREEZE!
Cd93
AA4.1
Flow Cytometry
FITC
Rat
Mouse
O89103
17064
IgG2b κ
Affinity chromatography
Antibody
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