missing translation for 'onlineSavingsMsg'
Learn More

CD71 (Transferrin Receptor) Monoclonal Antibody (R17217 (RI7 217.1.4)), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

720.00 NOK - 1348.00 NOK

Specifications

Antigen CD71 (Transferrin Receptor)
Clone R17217 (RI7 217.1.4)
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15279619
View Documents Promotion Details
Affymetrix eBioscience
13-0711-82
100 μg
1348.00 NOK
100µg
View alternative products
Save Up to 
»
Estimated Shipment: 08-05-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15269619
View Documents Promotion Details
Affymetrix eBioscience
13-0711-81
50 μg This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A View alternative products
Save Up to 
»
Description

Description

Description: The R17217 monoclonal antibody reacts with mouse CD71, a 170-180 kDa type II transmembrane protein. CD71, the transferrin receptor, exists as a homodimer on the cell surface and is essential for cellular growth. CD71 is expressed by immature proliferating cells and at low levels on resting mature lymphocytes. Antigen or mitogen stimulation of T and B cells upregulates the expression of CD71. Expression level differences have been observed in different mouse strains. Applications Reported: This R17217 antibody has been reported for use in flow cytometric analysis. Applications Tested: This R17217 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Specifications

Specifications

CD71 (Transferrin Receptor)
0.5 mg/mL
Monoclonal
Liquid
RUO
Q62351
IgG2a κ
Affinity chromatography
Antibody
R17217 (RI7 217.1.4)
Flow Cytometry
Biotin
Rat
Mouse
22042
Primary
4° C, store in dark, DO NOT FREEZE!
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.