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CD71 (Transferrin Receptor) Mouse, anti-Human, APC, Clone: OKT9, STEMCELL Technologies
Mouse Monoclonal Antibody
2146.81 NOK - 4520.39 NOK
Specifications
| Antigen | CD71 (Transferrin Receptor) |
|---|---|
| Clone | OKT9 |
| Applications | Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence |
| Classification | Monoclonal |
| Conjugate | APC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17109051
|
Stemcell Technologies
60106AZ.1 |
25 Tests |
2146.81 NOK
25 tests |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17199041
|
Stemcell Technologies
60106AZ |
100 Tests |
4520.39 NOK
100 tests |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- The OKT9 antibody reacts with CD71 (transferrin receptor), an ∼180 - 190 kDa disulfide-bonded homodimer and type 2 transmembrane glycoprotein expressed at high levels on a broad range of actively proliferating cells, as well as reticulocytes, monocytes, macrophages and marrow stromal cells
- Surface levels are low on resting leukocytes but are upregulated on lymphocytes, monocytes and macrophages following antigen or mitogen stimulation
- Expression is lost during differentiation of reticulocytes into mature erythrocytes
- CD71 mediates uptake of transferrin–iron complexes through receptor-mediated endocytosis and recycling of the apotransferrin–receptor complex to the cell surface
- It has also served as a target for drug delivery
- The OKT9 antibody binds an epitope that reportedly overlaps with that of antibody clone CY1G4 but is distinct from the ligand binding site for transferrin
Specifications
| CD71 (Transferrin Receptor) | |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| APC | |
| Human | |
| Primary |
| OKT9 | |
| Monoclonal | |
| Mouse | |
| IgG1 κ |