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CD274 (PD-L1, B7-H1) Rat anti-Mouse, Clone: MIH5, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5982-81

Additional Details : Weight : 0.01000kg

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Product Code. 15267657

  • 554.00 NOK / 50µg


Estimated Shipment date
from Supplier 26-08-2019
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Description

Description

Filtration: 0.2 μm post-manufacturing filtered. Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifications

Specifications

CD274 (PD-L1, B7-H1)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9EP73
B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1, programmed cell death 1 ligand 1, programmed death ligand 1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization, Western Blot
MIH5
Unconjugated
Cd274
Liquid
Cd274
IgG2a, lambda
50 μg
4° C
Primary
60533
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For Research Use Only.