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CD273 (B7-DC) Rat anti-Mouse, Clone: TY25, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5986-85

Additional Details : Weight : 0.01000kg

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Product Code. 15267667

  • 2690.00 NOK / 500µg


Estimated Shipment date
from Supplier 26-08-2019
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Description

Description

A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Specifications

Specifications

CD273 (B7-DC)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9WUL5
B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization, Western Blot
TY25
Unconjugated
Pdcd1lg2
Liquid
Pdcd1lg2
IgG2a, kappa
500 μg
4° C
Primary
58205
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