CD267 (TACI) Mouse anti-Human, Clone: 11H3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9217-82
Additional Details : Weight : 0.01000kg
DescriptionMembers in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
|PBS with 0.09% sodium azide; pH 7.2|
|CD267, CVID, CVID2, TACI, TNFRSF14B, transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B|
|Flow Cytometry, Functional Assay|
For Research Use Only.