CD217 (IL-17Ra) Rat anti-Mouse, PE, Clone: PAJ-17R, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 12-7182-82
Additional Details : Weight : 0.25000kg
DescriptionThis staining with PAJ-17R is not detected in IL-17RA knock-out mice. Applications Reported: This PAJ-17R antibody has been reported for use in flow cytometric analysis. Applications Tested: This PAJ-17R antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|interleukin 17 receptor A; AW538159; Cdw217; IL17r; VDw217; interleukin 17 receptor|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.