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CD205 Rat anti-Mouse, PerCP-eFluor™ 710, Clone: 205yekta, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-2051-80

Additional Details : Weight : 0.25000kg

Product Code. 15371300

  • 1092.00 NOK / 25µg


Estimated Shipment date
from Supplier 03-05-2019
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Description

Description

Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Specifications

Specifications

CD205
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q60767
RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
205yekta
PerCP-eFluor™ 710
Ly75
Liquid
Ly75
IgG2a, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
17076
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