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CD132 Monoclonal Antibody (TUGh4), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-1329-82
1396.73 NOK valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Additional Details : Weight : 0.25000kg
Description
Description: This TUGh4 monoclonal antibody reacts with human CD132, the common gamma chain (gamma c) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. This approximately 65 kDa receptor component is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. Mutations in the human gamma chain gene result in X-linked severe combined immunodeficiency (XSCID), a disease characterized by T cell deficiency leading to impairment of cell-mediated and humoral immunity. Applications Reported: This antibody has been reported for use in flow cytometric analysis. Applications Tested: This TUGh4 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.Specifications
CD132 | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P31785 | |
IL2RG | |
Affinity chromatography | |
RUO | |
3561 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
TUGh4 | |
Biotin | |
IL2RG | |
[g]c; Ab2-183; CD132; CD132 antigen; CIDX; common cytokine receptor gamma chain; cytokine receptor common subunit gamma; gamma(c); gammaC; gc; IL-2 receptor subunit gamma; IL2R gamma; IL-2R subunit gamma; IL2RG; IL-2RG; IMD4; interleukin 2 receptor subunit gamma; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); interleukin 2 receptor, gamma chain; Interleukin-2 receptor subunit gamma; p64; SCIDX; SCIDX1 | |
Rat | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2b λ |
For Research Use Only.