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CD132 Monoclonal Antibody (TUGh4), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

932.00 NOK - 2095.00 NOK

Specifications

Antigen CD132
Clone TUGh4
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15269719
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Affymetrix eBioscience
13-1329-82
100 μg
2095.00 NOK
100µg
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15259719
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Affymetrix eBioscience
13-1329-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: This TUGh4 monoclonal antibody reacts with human CD132, the common gamma chain (gamma c) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. This approximately 65 kDa receptor component is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. Mutations in the human gamma chain gene result in X-linked severe combined immunodeficiency (XSCID), a disease characterized by T cell deficiency leading to impairment of cell-mediated and humoral immunity. Applications Reported: This antibody has been reported for use in flow cytometric analysis. Applications Tested: This TUGh4 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
Specifications

Specifications

CD132
0.5 mg/mL
Monoclonal
Liquid
RUO
P31785
IL2RG
Primary
4° C, store in dark, DO NOT FREEZE!
IL2RG
TUGh4
Flow Cytometry
Biotin
Rat
Human
3561
IgG2b λ
Affinity chromatography
Antibody
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