CD126 Rat anti-Mouse, PE-Cyanine7, Clone: D7715A7, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 25-1261-80
Additional Details : Weight : 0.09500kg
DescriptionLight sensitivity: This tandem dye is sensitive to photo- induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488-561 nm; Emission: 775 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991, IL6R|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.