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ACROBiosystems Biotinylated Human IL-23 R Protein, Fc, Avitag™

Biotinylated Protein

5297.56 NOK - 23309.24 NOK

Specifications

Accession Number NP_653302.2
Molecular Weight (g/mol) 66.3 kDa
Source Biotinylated Human IL-23 R, Fc,Avitag (ILR-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 355 (Accession # Q5VWK5-1).
Immunogen Gly 24 - Gly 355
Storage Requirements -20°C
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16447779
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ACROBiosystems
ILR-H82F3-25UG
25 μg
5297.56 NOK
25µg
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Estimated Shipment: 10-04-2024
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16437779
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ACROBiosystems
ILR-H82F3-200UG
200 μg
23309.24 NOK
200µg
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Estimated Shipment: 10-04-2024
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Description

Description

Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 66.3 kDa. The protein migrates as 95-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_653302.2
Biotinylated Human IL-23 R, Fc,Avitag (ILR-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 355 (Accession # Q5VWK5-1).
-20°C
IL-23 R
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
MABSol™ Biotin Labeled Proteins
66.3 kDa
Gly 24 - Gly 355
IL-23 R,IL-23 Receptor
Precision Avi
Fc Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
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