BCL6 Mouse anti-Human, PerCP-eFluor™ 710, Clone: BCL-UP, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 46-9880-41
Additional Details : Weight : 0.23750kg
BeschreibungA test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PerCP-eFluor® 710 can be used in place of PE-Cy5, PE-Cy5.5 or PerCP-Cy5.5. PerCP-eFluor® 710 emits at 710 nm and is excited with the blue laser (488 nm). Please make sure that your instrument is capable of detecting this fluorochrome. For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin′s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt′s lymphomas and in nodular, lymphocyte predomit Hodgkin′s disease.
|PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2|
|B-cell lymphoma 6 protein; BCL-6; Zinc finger protein 51; LAZ-3 protein; BCL-5; Zinc finger and BTB domain-containing protein 27; ZNF51; ZBTB27; LAZ3; BCL5; BCL6|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.