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Invitrogen™ ACVR2A Human Protein
Easily screen for kinase binding. Thermo Fisher Invitrogen™ ACVR2A Human Protein recombinant fusion protein consists of full-length activin A receptor kinase and a glutathione S-transferase (GST) tag. It is validated in the LanthaScreen™ Eu Kinase Binding Assay.
5160.00 NOK - 67200.00 NOK
Specifications
| Accession Number | NP001607.1 |
|---|---|
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% NP-40, 2mM DTT and 50% glycerol. |
| Molecular Weight (g/mol) | 85.3kDa |
| Storage Requirements | Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
| Structural Form | Full Length |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
11310872
|
Invitrogen™
PV6124 |
10μg |
5160.00 NOK
Each |
Estimated Shipment: 02-05-2024 Log in to see stock. |
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|
15458713
|
Invitrogen™
PR9111A |
100μg |
16010.00 NOK
100µg |
Estimated Shipment: 10-05-2024 Log in to see stock. |
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|
15418813
|
Invitrogen™
PV6125 |
1mg |
67200.00 NOK
1mg |
Estimated Shipment: 02-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The LanthaScreen™ Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measurements and makes simple the study of type III (allosteric) inhibitors.
The LanthatScreen™ Eu Kinase Binding Assay is easy to optimize and run. The assay uses a simple mix-and-read format with a single one-hour incubation and no development steps. Simultaneous binding of an Alexa Fluor™ conjugate or tracer” to a tagged kinase is detected by addition of a europium-labeled anti-tag antibody, in this case anti-GST. Simultaneous binding of the tracer and antibody to the kinase results in a high degree of fluorescence resonance energy transfer (FRET), while displacement of the tracer with a kinase inhibitor results in a loss of FRET.
- Compatible and validated with the LanthaScreen™ Eu Kinase Binding Assay
- Expressed in insect cells
- GST tagged for use with Eu-labeled GST antibody
- No special measures were taken to activate this kinase
ACVR2A for the LanthaScreen Kinase Binding Assay
Activin A receptor kinase (ACVR2A) is a type II member of the TGF-beta family of receptor Serine/Threonine kinases. ACVR2A is involved in the activin and myostatin signaling pathway. (ACVR2A Aliases: ACVR2, ACTRII).
This insect cell-expressed recombinant fusion protein of full-length ACVR2A and GST tag has been validated in the LanthaScreen™ Eu Kinase Binding Assay with the Tracer 236 and Eu-labeled GST reagents.
Specifications
| NP001607.1 | |
| 85.3kDa | |
| Full Length | |
| STKR Kinase Family | |
| Recombinant | |
| Baculovirus |
| 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% NP-40, 2mM DTT and 50% glycerol. | |
| Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. | |
| ACVR2A, ACTR2, ACTRII, ACVR2 | |
| Human | |
| GST Tag | |
| Frozen |