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17-(Allylamino)-17-demethoxygeldanamycin, 99%, Thermo Scientific Chemicals
1125.65 NOK valid until 2024-03-29
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Quantity:
25 mg
100 mg
200 mg
Description
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.
Solubility
Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.
Solubility
Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications
Melting Point | 207°C to 209°C |
Flash Point | >110°C (230°F) |
Quantity | 25 mg |
Sensitivity | Light sensitive |
Solubility Information | Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/ml; Very poorly soluble in water |
Formula Weight | 585.69 |
Percent Purity | 99% |
Physical Form | Solid |
Chemical Name or Material | 17-(Allylamino)-17-demethoxygeldanamycin |
RUO – Research Use Only
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